Difference between revisions of "Solubis plugin for YASARA"
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<big>'''Welcome to the homepage of the Solubis plugin for YASARA'''</big> [[File:solubispluginyasara.jpg|thumb|500px|Solubis tools menu in YASARA]] | <big>'''Welcome to the homepage of the Solubis plugin for YASARA'''</big> [[File:solubispluginyasara.jpg|thumb|500px|Solubis tools menu in YASARA]] | ||
| − | The Solubis plugin for YASARA is a software package to identify mutants that decrease the aggregation tendency with YASARA. This package combines TANGO | + | The Solubis plugin for YASARA is a software package to identify mutants that decrease the aggregation tendency with YASARA. This package combines TANGO, FoldX and YASARA. |
'''TANGO''' is a statistical mechanics algorithm that identifies the regions of a protein sequence involved in the process of b-sheet aggregation. | '''TANGO''' is a statistical mechanics algorithm that identifies the regions of a protein sequence involved in the process of b-sheet aggregation. | ||
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'''FoldX''' is a molecular modeling and protein design software program that calculates energy differences that come close to experimental values. FoldX is widely used to predict the effect of mutations on the stability of a protein. | '''FoldX''' is a molecular modeling and protein design software program that calculates energy differences that come close to experimental values. FoldX is widely used to predict the effect of mutations on the stability of a protein. | ||
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'''YASARA''' is a molecular-graphics, -modeling and -simulation program that finally makes it really easy to answer your biological questions. The 3D graphics and intuitive interface make it a very user-friendly protein and nucleic acid analysis package. It is also easily extendable by means of plugins. | '''YASARA''' is a molecular-graphics, -modeling and -simulation program that finally makes it really easy to answer your biological questions. The 3D graphics and intuitive interface make it a very user-friendly protein and nucleic acid analysis package. It is also easily extendable by means of plugins. | ||
| − | FoldX | + | FoldX and TANGO are normally run from the command line without graphics. By installing the SOLUBIS plugin for YASARA, you can access these tools at the touch of a button in the 3D graphical YASARA interface. You directly see the results of your FoldX protein analysis on screen. |
| − | TANGO | + | TANGO, FoldX, YASARA and the Solubis plugin for YASARA are all available for Linux, MacOSX and Windows. |
This website is a guide through the installation and usage of the Solubis plugin for YASARA. | This website is a guide through the installation and usage of the Solubis plugin for YASARA. | ||
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== Miscellaneous == | == Miscellaneous == | ||
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* [[Citing|Citing the plugin]] | * [[Citing|Citing the plugin]] | ||
* [[Contact|Contact and support]] | * [[Contact|Contact and support]] | ||
== Download == | == Download == | ||
| − | * [[Media: | + | * [[Media:SolubiSyasara.zip|Solubis plugin for YASARA]] (needs YASARA version 12.2.20 or higher) |
== FoldX version information == | == FoldX version information == | ||
| − | + | FoldX 3 Beta 6 is required for the plugin to work. Any FoldX release before January 2014 will not work. Get the current version from [http://foldx.crg.es http://foldx.crg.es]. | |
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== YASARA version information == | == YASARA version information == | ||
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== Links == | == Links == | ||
* [http://tango.crg.es tango.crg.es] TANGO website | * [http://tango.crg.es tango.crg.es] TANGO website | ||
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* [http://foldx.crg.es foldx.crg.es] FoldX website | * [http://foldx.crg.es foldx.crg.es] FoldX website | ||
* [http://www.yasara.org www.yasara.org] YASARA website | * [http://www.yasara.org www.yasara.org] YASARA website | ||
* [http://www.switchlab.org www.switchlab.org] Switch Laboratory | * [http://www.switchlab.org www.switchlab.org] Switch Laboratory | ||
* [http://www.python.org www.python.org] Python website | * [http://www.python.org www.python.org] Python website | ||
Latest revision as of 15:43, 8 December 2014
Welcome to the homepage of the Solubis plugin for YASARA
The Solubis plugin for YASARA is a software package to identify mutants that decrease the aggregation tendency with YASARA. This package combines TANGO, FoldX and YASARA.
TANGO is a statistical mechanics algorithm that identifies the regions of a protein sequence involved in the process of b-sheet aggregation.
FoldX is a molecular modeling and protein design software program that calculates energy differences that come close to experimental values. FoldX is widely used to predict the effect of mutations on the stability of a protein.
YASARA is a molecular-graphics, -modeling and -simulation program that finally makes it really easy to answer your biological questions. The 3D graphics and intuitive interface make it a very user-friendly protein and nucleic acid analysis package. It is also easily extendable by means of plugins.
FoldX and TANGO are normally run from the command line without graphics. By installing the SOLUBIS plugin for YASARA, you can access these tools at the touch of a button in the 3D graphical YASARA interface. You directly see the results of your FoldX protein analysis on screen.
TANGO, FoldX, YASARA and the Solubis plugin for YASARA are all available for Linux, MacOSX and Windows.
This website is a guide through the installation and usage of the Solubis plugin for YASARA.
Have fun!
Topics in this guide
Miscellaneous
Download
- Solubis plugin for YASARA (needs YASARA version 12.2.20 or higher)
FoldX version information
FoldX 3 Beta 6 is required for the plugin to work. Any FoldX release before January 2014 will not work. Get the current version from http://foldx.crg.es.
YASARA version information
The plugin only works properly from YASARA version 12.2.20 and higher. Upgrading to the latest YASARA is strongly recommended.
Links
- tango.crg.es TANGO website
- foldx.crg.es FoldX website
- www.yasara.org YASARA website
- www.switchlab.org Switch Laboratory
- www.python.org Python website
